In recent years the Caribbean Region has seen an increase in the number and severity of emergencies, natural disasters and threats to the public health. Devastating hurricanes and earthquakes have impacted many islands in the region in recent years. Political unrest inside and outside the region has resulted in an influx of people seeking safety away from their homes. Lately there has been a sharp increase in the spread of infectious diseases like ZIKA, Chikungunya, and Dengue. Additionally, as the world shrinks and travel increases, the threat of spreading infectious diseases like SARS, EBOLA, MERS-CoV and others increases. CARPHA is poised to respond anywhere in the Region to those in need.