O-05 A retrospective study of five-year survival rates of women diagnosed with and treated for cervical cancer between 2012 and 2016 at the Georgetown Public Hospital Corporation

Methods: A retrospective cohort study of patients’ charts from the Georgetown Public Hospital Gynaecology Outpatient Department was conducted for 2012 to 2016. All patients diagnosed at the hospital with cervical cancer during the study period were included in analyses. Survival data was extracted from charts or using contact information provided in charts if there was loss to follow-up. Additional data collected included demographic features, disease stage, presence of comorbidities, smoking and alcohol habits, and treatment received. Frequency and survival analyses were conducted using Stata IC 16.

Results: The mean age of study participants was 54 years, and there was a predominance of Indo-Guyanese (34.1%) followed by Afro-Guyanese (29.5%). Of the patients 20.5% had a pap smear done and 13.6% had visual inspection with acetic acid done prior to diagnosis. In terms of diagnosis, 11.4% presented with stage 1 disease, 50% with stage 2, 31.8% with stage 3 and 6.8% with stage 4. The five-year overall survival rate was 38.6%. Survival rates ranged from 60% in stage 1 disease to 0% in stage 4 disease. A regression model showed no association was between survival and disease stage when controlling for comorbidities, treatment received and age, Increasing age was the only significant predictor of dying from cervical cancer (OR 1.06, 95% CI 1.01, 1.10).

Conclusion: Survival decreases with increasing age, indicating a need for patient education and early diagnosis through regular programmes to increase five-year survival rates.