O-28 Prevalence, Patterns, and Self-reported Impacts of Cognitive Enhancer Use Among Medical Students at the University of Guyana

Methods: A descriptive, observational, cross-sectional study was conducted among 162 medical students at the University of Guyana, School of Medicine, selected via simple random sampling. A structured, 25-item online questionnaire was distributed via email. Quantitative data were analyzed using SPSS v22.0. Descriptive statistics were used to calculate frequencies and percentages, while chi-square tests assessed associations between CE use and demographic variables. P-values were computed for statistical significance while the qualitative responses underwent thematic analysis. Ethical approval was obtained, and confidentiality was maintained.

Results: Based on the 162 responses, there was a 53.1% prevalence of CE usage. Caffeine-based products were the most frequently consumed enhancers. These include coffee (70.9%) and energy drinks 55.8%) while Adderall and L-Tyrosine were the least consumed (1.16% respectively). Primary motivations included enhanced energy levels (82.6%), management of increased academic workload (57%), enhanced memory and concentration (54.7%), and stress alleviation (24.4%). For 32.7% of users, perceived benefits surpassed risks, while 64% reported awareness of potential adverse effects. CE use was more prevalent among female students (67.4%) and those aged 22-25 years (62.4%). Statistical analysis showed no significant associations between demographic factors (gender, age, academic year, work status) and CE use (p > 0.05). However, significant associations were found between caffeinated CE use and reported side effects, including tachycardia (p = 0.002), insomnia (p = 0.006), and anxiety (p = 0.006).

Conclusion: This investigation revealed a substantial prevalence of CE use among medical students, primarily driven by academic demands and stress management needs. The findings underscore the necessity for initiatives addressing the risks and implications of CE use.