O-40 A comparison of fertility and quality of life outcomes between women who had undergone laparoscopic vs. abdominal myomectomy at The University Hospital of the West Indies during the years 2016-20

Methods: A retrospective cross-sectional study was conducted on 94 patients who had abdominal and laparoscopic myomectomy at the University Hospital of the West Indies between January 2016 and February 2024. Women aged 18–45 years were included. Data was collected via medical records and interviewer-administered questionnaires, including the Patient-Reported Outcomes Measurement Information System (PROMIS) for quality assessment. Differences by group were done by t-test and associations by logistic regression.

Results: The mean (sd) age for the women was 38.9 (5.2) years, and the mean (sd) BMI was 28.3 kg/m2 (5.9). There were no statistically significant differences in age, and anthropometric variables (weight and height) between the groups. There was no statistically significant difference in the post procedure adjusting for their pregnancy proportion by surgical group. The p=0.359. The surgical group meaning abdominal or laparoscopic myomectomy. However, patients in the laparoscopic group had significantly greater physical function (p=0.042), less intraoperative blood loss (p<0.0001), and shorter hospital stays (p<0.0001). No significant differences were observed in QOL domains such as anxiety, depression, and pain interference.

Conclusion: Fertility outcomes were not different between women who had laparoscopic and abdominal myomectomy. However, laparoscopic myomectomy was associated with better physical function, less blood loss, and shorter hospital stays. These findings support laparoscopic myomectomy as a favourable option for patients seeking improved postoperative recovery and minimal morbidity without compromising fertility.