P-03 The Caribbean Cure? Exploring Irish sea moss as a natural remedy for autoimmune conditions, hypertension, and gut health
Author(s):
J Joseph
Country(ies) Of Focus:
- CARPHA Member States
- CARICOM Countries
Year of Presentation:
2026
Objective: To conduct a systematic review of literature
evaluating in vivo animal and in vitro evidence on the
effects of Irish sea moss (Chondrus crispus) on gut microbiota modulation, inflammatory and immune responses, and
potential mechanisms relevant to gastrointestinal, cardiovascular, and autoimmune health.
Methods: A systematic literature search was conducted using the PubMed database which focused on studies that were published up to 2025. Inclusion criteria for this review included studies published in English that were primary research studies involving animal models or in vitro experiments. Priority was given to studies that used human cell lines or in vivo animal models to better reflect translational relevance. The search was conducted using the terms: “Chondrus crispus AND (inflammatory OR gut OR blood pressure).”
Results: A total of 292 articles were identified, with four primary studies meeting inclusion criteria. Two in vivo and two in vitro studies reported significant increases in shortchain fatty acid production, improved immune markers, reduced inflammatory cytokine expression, and favorable modulation of the gut microbiota. No studies assessed blood pressure regulation or comparisons with pharmaceutical therapies.
Conclusion: Irish sea moss (Chondrus crispus) is traditionally used for its perceived health benefits; however, scientific evaluation of its effects on gut health, blood pressure, and autoimmune symptoms remains limited. In vivo and in vitro findings support the hypothesis that Irish sea moss may improve gut microbiota balance and reduce inflammation. While current evidence seems promising, especially in comparison with pharmaceutical mechanisms, further human clinical trials are required to validate its translational potential as a complementary or alternative therapy.