P-12 Review of the Pathophysiology of the Vasa Vasoroum of the pulmonary vessels in Covid19: The major vessels involved in pulmonary thromboembolism in COVID-19.
Author(s):
H Daisley, O Acco , M Daisley , L Paul , E James , A Rampersad , A Ramdin , F Narinesingh , O Humphrey , M Nathan , D George
Year of Presentation:
2023
Objective: Pulmonary thromboembolism is a major pathological event seen in COVID-19. There were many reports in medical literature in which the source of pulmonary thromboembolism was indeterminate. Our main objective was to identify the pathophysiology of pulmonary thromboembolism in COVID-19.
Methods: Autopsies were performed on patients who died of COVID-19 and histopathological examination was done on all tissues.
Results: The lung showed among other changes, thrombosis of the vasa vasoroum of the large pulmonary vessels. Thrombosis of the vasa interna was also noted. Thromboembolism of the large pulmonary vessels was seen to be originating from the thrombus of the vasa interna in all autopsied cases.
Conclusion: Thromboembolism of the major pulmonary artery arises from thrombosis of the vasa vasoroum interna. This is the major pathophysiological process which accounts for the frequent pulmonary thromboembolism seen in COVID-19.