P-14 Bloodstream infections among patients admitted to the department of internalmedicine, Georgetown Public Hospital Corporation.
Author(s):
A Edun , D Persaud
Year of Presentation:
2024
Objective: To determine the incidence of bloodstream infections in patients admitted to the internal medicine department, GPHC over a one-year period, and to identify the common organisms isolated from blood cultures, their antimicrobial susceptibility patterns as well as the admitting diagnoses and comorbidities of these patients.
Methods: A retrospective cross-sectional analysis of 180 positive blood culture isolates received over a one-year period was done. Pertinent data were collected from the blood culture logbook at the microbiology section, GPHC laboratory and patient charts from the medical records department. Incidence was calculated and the IBM SPSS analytical software was utilized for data analysis and identifying statisticallu significant relationships.
Results: The incidence of bloodstream infections was 2.2%. Enterococcus sp. (GPC) was found to be the most common microorganism isolated (12.5%), while Pseudomonas sp. (GNB) and MRSA (GPC) accounted for 11.9% and 10.4% respectively. Many positive cultures demonstrated multi-drug resistance (MDR) to aminoglycosides (8.5% to 11.7%), penicillins (13.2% to 14.9%) and cephalosporins (8.5% to 20.2%). Admitting diagnoses included commu- nity acquired pneumonia, urosepsis, catheter related blood stream infection among others. Diabetes Mellitus (28%) and hypertension (27%) were the 2 most common comor- bidities. Chronic kidney disease was present in 13% cases, while 8% of patients had no comorbidities.
Conclusion: Findings demonstrate multi-drug resistance amongst commonly identified isolates and show that patients with comorbidities have a higher risk to develop bacteremia. As a response to these challenges, implementa- tion of robust infection control practices and an antibiotic stewardship program should be of priority at GPHC.