P-14 The outcomes of cervical cerclage with antibiotic use at Victoria Jubilee Hospital Jamaica
Author(s):
M. Archer , C. Rattray , R. Chand
Year of Presentation:
2023
Objective: To assess how cervical cerclage with antibiotic use effects maternal and foetal outcomes.
Methods: This study was a retrospective cohort study that analyzed the clinical data of pregnant women who received cervical cerclage at The Victoria Jubilee Hospital, Jamaica between 2010 and 2021. After Ethics approval was obtained, data was extracted from the patients’ dockets using a data extraction sheet. Data was analyzed using students T test, chi-square and multivariate logistic regression.
Results: 200 patients with cervical cerclage were analyzed: 100(50%) received antibiotics and 100(50%) did not. There was a significant increase in the latency period in the antibiotic group of 20(+/-5) weeks compared to 17(+/-7) weeks without antibiotics(p<0.005). The mean gestational age at delivery was improved at 37(+/-3) weeks with antibiotic compared to 34(+/-6) weeks without antibiotics. There was an improved birth weight of 2.89(+/-0.785) with antibiotic use(p<0.05). The number of admissions to nursery and respiratory distress rates were reduced in the antibiotic group (p<0.001). The use of antibiotics reduced the percentage of neonates that died from 20% to 4%(p<0.001).
Conclusion: The use of antibiotics with cervical cerclage has demonstrated significant improvements in the latency period from cerclage placement to delivery, delivery at term, as well as reductions in preterm births, admissions to nursery and neonatal death.