P-48 Epidemiological Trends and Clinical Correlation of Dengue Cases at Georgetown Public Hospital Corporation
Author(s):
N Narine, G Rambaran
Year of Presentation:
2025
Objective: To investigate the incidence of Dengue cases at
Georgetown Public Hospital Corporation (GPHC) .
Methods: This was a retrospective cross-sectional study designed to determine the incidence of Dengue during the period January- December 2023 at the GPHC. This study included 181 patients with admitted and/or final diagnosis of Dengue. The tool used included the patient’s demographic information, symptoms, Dengue serology, days of onset and resolution of symptoms, and pre-clinical findings.
Results: The incidence of Dengue was approximately 5.65 cases per 1,000 people in 2023. Females accounted for 55.% of cases, while males comprised 45%. African (38.%) and East Indian (33.%) groups were most affected. Region 4 accounted for the majority (58.0%). The 13–24 age group had the highest incidence (50.8%), followed by the 25–35 age group (19.3%). Risk factors included smoking (11.0%), alcohol consumption (8.3%), hypertension (9.9%), and diabetes mellitus (5.0%). Serology results showed IgM + IgG positivity in 43.6% of cases, IgG alone in 29.8%, and IgM alone in 22.1%. The NS1 antigen test was positive in 4.4%. Fever was the most prevalent symptom (82.9%), followed by vomiting (55.2%) and headache (30.9%). There was no statistically significant association between platelet count and bleeding symptoms (p>0.05).
Conclusion: The higher incidence among young adults and females contrasts with global patterns, emphasizing the need for region-specific public health interventions. Dengue remains a significant public health concern in Guyana, with an incidence rate of 5.65 cases per 1,000 people in 2023.