As deaths from COVID-19 surpass one million worldwide, with 4,194 reported in 33 territories of the Caribbean (as of October 15, 2020), including CARPHA Member States, the growing need for a vaccine to prevent illness and death has become painfully evident. It is critical that there is equitable access to COVID-19 vaccines to allow for adequate coverage and a safe approach to achieving herd immunity as no country will be safe until everybody is safe.