P-53 Treatment of Infantile Haemangioma with Atenolol when Propranolol causes a Rare Side Effect: A Case Presentation
Author(s):
N L McKenzie , M L Edwards
Year of Presentation:
2025
Objective: To determine the safety and efficacy of atenolol
in the treatment of a case with high-risk infantile hemangioma when propranolol causes a rare side effect.
Methods: A 6-week-old male preterm infant diagnosed with high risk infantile haemangioma to the right palpebral temporal region, commenced treatment with oral propranolol at 2.5mg/kg daily in 2 divided doses. After 3 days he had a body temperature of 39 degrees C, which continued every time he was given propranolol. Propranolol was discontinued and he was then placed on atenolol at 1mg/kg daily with follow up at 3, 6 and 12 months.
Results: Preterm infant with high risk infantile haemangioma who developed temperature instability (a rare side effect during treatment with propranolol) had complete resolution when treated with atenolol with no side effects.
Conclusion: More research is needed to determine generalisable determinants of case, however this high risk infantile haemangiomas case can be successfully and safely treated with atenolol when propranolol is contraindicated.