Objective: Cancer registration activities in English-speaking Caribbean countries would benefit from improvements to the information technology (IT) application and infrastructure currently in use. In 2020, in response to these identified regional needs, the International Agency for Research on Cancer (IARC) Caribbean Cancer Registry Hub, based at the Caribbean Public Health Agency (CARPHA), began investigating possible alternative IT applications. As a result, a collaborative project developed between IARC, CARPHA, the University of Oslo and the Rwanda National Cancer Registry. Over the period March-October 2022, the DHIS2 Oncology Module – which was developed by the Rwanda National Cancer Registry - was installed, customized, and tested at CARPHA.